Significant hormonal changes associated with menopause might affect cognitive function in addition to physical and emotional well-being. According to new research, the menopausal transition may affect dementia risk, especially due to changes in estrogen levels and how they affect the brain. With a focus on recognizing midlife cognitive changes, evaluating dementia risk, and incorporating preventive measures into clinical practice, this course investigates the biological mechanisms that connect menopause and brain aging.
Dr. Roberta D. Brinton is director of the University of Arizona Health Sciences’ Center for Innovation in Brain Science, where she leads research on Alzheimer’s, the aging female brain, and regenerative therapeutics. A renowned neuroscientist with continuous NIH funding for over 20 years, she previously held multiple professorships at the University of Southern California and directed key neuroscience research and translational programs. Dr. Brinton has published more than 160 peer-reviewed articles, delivered over 250 invited presentations worldwide, and co-founded CoCensys, a biotechnology company focused on neurological and psychiatric therapies. She serves on national scientific review boards, including for the NIH and Alzheimer’s foundations, and has received numerous honors, including the Presidential Citizens Medal from President Barack Obama, recognition as one of U.S. News & World Report’s “Ten Best Minds,” and Woman of the Year by Los Angeles magazine. A University of Arizona alumna, she earned her PhD in neuropharmacology and psychobiology and completed NIH postdoctoral research at Rockefeller University before becoming an internationally recognized leader in neuroscience and STEM education.
Learning Objectives
- List 6 or more modifiable risk factors for dementia
- Evaluate interventions, including hormonal and lifestyle approaches, that may support brain health during and after menopause
- Summarize the current evidence linking menopause and increased dementia risk
- Identify special considerations for high-risk populations