Biomarkers

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ResearchersAgainstAlzheimer's would like to thank Roche Diagnostics for their support of this project.

Summary of Biomarker Analysis

  • Method of Measurement

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  • Biomarker Measured

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  • Biomarker Categories

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Summary completed October 2019

Biomarkers for Alzheimer’s Disease

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  • Biomarker
Biomarker
Multi-modal Neuroimaging
Biomarker Measured
Blood/Plasma, Imaging, CSF
Method of Measurement
Amyloid
Use
Diagnostic, Susceptibility/risk
Stage of Development
Clinical trials
Biomarker
Plasma putative biomarkers (i.e. Ab40 amyloid and total Ab42 amyloid, free, bound, free/bound, truncated, sAPPα) (BALTAZAR)
Biomarker Measured
Blood/Plasma
Method of Measurement
Amyloid
Use
Diagnostic, Prognostic, Predictive
Stage of Development
Clinical trials
Biomarker
Fatty acid binding protein 3 (FABP3)
Biomarker Measured
CSF
Method of Measurement
Neuronal damage
Use
Diagnostic
Stage of Development
Clinical trials
Biomarker
Eye Tracking in Reading (ADAL)
Biomarker Measured
Optical
Method of Measurement
Eye movement
Use
Diagnostic
Stage of Development
Clinical trials
Biomarker
Florbetapir F18 AV45 F18
Biomarker Measured
Imaging
Method of Measurement
Amyloid
Use
Diagnostic
Stage of Development
Clinical trials
Biomarker
Florbetaben (FBB ACC)
Biomarker Measured
Imaging
Method of Measurement
Amyloid
Use
Unknown
Stage of Development
Clinical trials
Biomarker
Ferritin
Biomarker Measured
Imaging, CSF
Method of Measurement
Brain iron levels
Use
Monitoring, Susceptibility/risk
Stage of Development
Clinical trials
Biomarker
Flortaucipir (AV1451)
Biomarker Measured
Imaging
Method of Measurement
Tau
Use
Diagnostic
Stage of Development
Clinical trials
Biomarker
Interleukin 1β (IL- 1β) (plasma)
Biomarker Measured
Blood/Plasma
Method of Measurement
Inflammation
Use
Diagnostic
Stage of Development
Clinical trials
Biomarker
Imaging Inflammation
Biomarker Measured
Imaging, CSF
Method of Measurement
Inflammation
Use
Prognostic
Stage of Development
Clinical trials
Biomarker
hFABP
Biomarker Measured
CSF
Method of Measurement
Neuronal damage
Use
Diagnostic
Stage of Development
Clinical trials
Biomarker
Eye movement and Retinal nerve fiber layer thickness (BEAM) (Pittsburgh Compound B [11C]-PIB)
Biomarker Measured
Optical
Method of Measurement
Vasculature
Use
Pharmacodynamic/response, Susceptibility/risk
Stage of Development
Clinical trials
Biomarker
Eye Movement Recording (MOMAD)
Biomarker Measured
Optical
Method of Measurement
Eye movement
Use
Diagnostic
Stage of Development
Clinical trials
Biomarker
Interleukin 6 (IL-6) (plasma)
Biomarker Measured
Blood/Plasma
Method of Measurement
Inflammation
Use
Diagnostic
Stage of Development
Clinical trials
Biomarker
Interleukin 10 (IL-10)
Biomarker Measured
Blood/Plasma
Method of Measurement
Inflammation
Use
Susceptibility/risk
Stage of Development
Clinical trials
Biomarker
Magnetoencephalography (MEG)
Biomarker Measured
Imaging
Method of Measurement
Cell signaling
Use
Diagnostic
Stage of Development
Clinical trials
Biomarker
MCP-1
Biomarker Measured
CSF
Method of Measurement
Inflammation
Use
Diagnostic
Stage of Development
Clinical trials
Biomarker
Metabolic Hyperspectral Retinal Camera (MHRC)
Biomarker Measured
Optical
Method of Measurement
Amyloid
Use
Diagnostic
Stage of Development
Clinical trials
Biomarker
Epileptiform Activity During REM Sleep
Biomarker Measured
Blood/Plasma, Imaging
Method of Measurement
Cell signaling
Use
Diagnostic
Stage of Development
Clinical trials
Biomarker
EEG Connectivity and Graph Theory Combined With ApoE Testing
Biomarker Measured
Imaging
Method of Measurement
Cell signaling
Use
Susceptibility/risk
Stage of Development
Clinical trials
Questions? Additional biomarkers to share? Contact Us