SNIFF: Study of Nasal Insulin to Fight Forgetfulness
- What do Participants Do?
- Read and sign a consent form.
- Give family and Medical History.
- Answer questions that test your memory, thinking, mood, and concentration.
- Complete a brief neurological examination.
- Give permission to review the medical records of the individual with memory and thinking problems.
- Provide a blood, urine and lumbar fluid sample.
- Receive a free ECG (a look at your heart)
- Have a study partner- someone who you see regularly who can answer questions about your health
- Monetary compensation may be available at certain sites
- Why is this Study Important?
- The purpose of the SNIFF study is to find out whether a type of insulin, when administered as a nasal spray, improves memory in adults with a mild memory impairment or Alzheimer’s disease. There is growing evidence that poor regulation of insulin may make it difficult for the brain to function optimally and may contribute to the development of Alzheimer’s. SNIFF will test a therapy aimed at using insulin to see if these deficiencies can be corrected.
- What are the study facts?
- Study participation is voluntary.
- Joining the study will not affect your healthcare or insurance.
- information is confidential.
- There is no cost to participate.
- A participant may withdraw from the study at any time.
- Travel to the research center is required for testing and follow-up.
- Participants will receive periodic updates from the Project Director
- Who can join the Study?
- Have a diagnosis of a mild cognitive impairment or possibly mild Alzheimer’s Disease
- Fluent in English or Spanish
- Have a partner available to attend all clinic appointments and available to supervise drug administration twice a day
- Stable medical condition for three months prior to screening visit
- Stable medications for four weeks prior to screening visit
- Do NOT take drugs for diabetes (type I or II)
- Willing and able to undergo clinic assessments (for example -- blood and urine lab tests, MRI, lumbar puncture, ECG, neuropsychological tests)
You may be eligible to join the SNIFF study if you:
- Enroll in the Study Today!
- List of study locations at bottom (need to have ability to link to each location with the name of the chief researcher.[SNIFF ADRC Page includes list of sites with numbers. Need to add a person’s name and email.
- Who is sponsoring this Study?
- This study is being conducted by the Alzheimer’s disease Cooperative Study (ADCS) through a grant from the National Institute on Aging (NIA), one of the National Institutes of Health (NIH).
- There are many other research studies available in throughout the United States. To learn more about these studies go to: [provide link to I’m in or the Clinical Trials Engagement Network]
|AZ||Phoenix||Banner Alzheimer's Institute||(602)839-6853|
|AZ||Sun City||Banner Sun Health Research Institute||(623)832.8790|
|CA||Irvine||University of California, Irvine||(949)824-8726|
|CA||La Jolla||University of California, San Diego||(858)246-1303|
|CT||New Haven||Yale University School of Medicine||(203)764-8106|
|FL||Jacksonville||Mayo Clinic, Jacksonville||(904)953-7989|
|FL||Tampa||University of South Florida - Health Byrd Alzheimer Institute||(813)974-4904|
|IL||Chicago||Rush University Medical Center||(312)563-4111|
|KS||Kansas City||University of Kansas||(913)945-7676|
|KY||Lexington||University of Kentucky||(859)323-3145|
|MA||Boston||Brigham and Women's Hospital||(617)732-8085|
|MD||Baltimore||Johns Hopkins University||(410)550-9053|
|MN||Rochester||Mayo Clinic, Rochester||(507)293-4726|
|MO||St. Louis||Washington University, St. Louis||(314)286-2683|
|NC||Winston-Salem||Wake Forest University Health Sciences||(336)713-8847|
|NY||New York||Mount Sinai School of Medicine||(212)659-8885|
|NY||New York||New York University Medical Center|
|NY||Rochester||University of Rochester Medical Center||(585)760-6562|
|OH||Cleveland||Case Western Reserve University||(216)464-6474|
|OR||Portland||Oregon Health & Science University||(503)494-9399|
|RI||Providence||Rhode Island Hospital||(401)444-2484|
|TX||Dallas||University of Texas, Southwestern MC at Dallas||(214)648-9331|
|TX||Houston||Baylor College of Medicine||(713)798-4734|
|WA||Seattle||University of Washington||(206)764-2339|