September 09, 2014

Today's Top Alzheimer's News

Meryl Comer's book bears witness to everything Alzheimer’s took from her husband and her family, Maine editorial calls for wandering system to help Alzheimer's sufferers, Biotechnology Industry Organization calls for large-scale multi-generational genome sequencing to fight diseases like Alzheimer's, and UCLA biologists say they have identified a gene that can slow the aging process when activated (read more). 

Must reads

  • A September 9, 2014 Forbes article highlighted Meryl Comer's Slow Dancing with a Stranger and the impact of Alzheimer's on women. According to the article, "If Alzheimer’s is about forgetting, Comer’s just released book, Slow Dancing with a Stranger, is about bearing witness to everything Alzheimer’s took from her husband and her family. Equally important, it’s a call to action for women who, as caregivers, are most often Alzheimer’s second victim. What distresses Comer is that there are no better options for women today around care than there were 20 years ago. There are still no disease-modifying drugs or treatments for Alzheimer’s, a fatal neurodegenerative disease that has no cure...If Comer’s work has made her a public face in the fight against Alzheimer’s (she is also co-founder of WomenAgainstAlzheimers), her new book Slow Dancing with a Stranger reveals the more personal side of her journey as caregiver to her husband and, more recently, also to her aging mother."
  • A September 9, 2014 Portland Press Herald editorial advocated for the use of tracking systems to help manage Alzheimer's wandering. According to the editorial, "The issues with diagnosis, care and costs related to Alzheimer’s disease are as difficult to solve as they are troubling. But wandering can be mitigated, simply and inexpensively, through programs that are now being used in some Maine communities and should be considered elsewhere.One of these programs, known as The Wanderers Database, is coming to four central Maine communities...If that person disappears, police can instantly call up and disseminate photographs and personal and medical information, allowing for a faster, more effective search…Alzheimer’s disease must be reckoned with in the coming years, in Maine as much as anywhere else. The number of Alzheimer’s cases in Maine, the nation’s oldest state, is expected to increase by almost 45 percent in the next six years alone.That comes with many long-term challenges, from attracting enough caregivers to figuring out how to pay for the astronomical Medicare costs associated with the disease. But with the tracking programs so readily available, the danger, and the anguish, presented by wandering can be abated now."
  • A September 8, 2014 The Hill opinion piece by Jim Greenwood called for "the development and execution of a large-scale, longitudinal study to sequence the genomes of 100,000 volunteers in age cohorts from those in their 20s through those in their 80s, obtain biospecimens and additional health care data from those individuals, and develop biological markers that may predict Alzheimer’s or other chronic diseases for which the cause is unknown or poorly understood." According to Greenwood, "This large-scale, long-range study will not only yield data necessary to find ways to cure and prevent Alzheimer’s, it would help researchers find ways to treat hundreds of other diseases for which we still lack adequate therapies…The urgency of finding a cure for Alzheimer’s cannot be overstated. It is difficult to find anyone whose life has not been affected by this devastating disease. Biotech holds the greatest promise for finding a cure. We must act now for the patients and their families who are counting on us." Greenwood is president and CEO of the Biotechnology Industry Organization.
Research, science, and technology 
  • A September 8, 2014 The Boston Globe article reported that a new study from the University of Massachusetts Medical School in Worcester found that "More than half of patients with advanced dementia who are in the end stages of Alzheimer’s disease continue to receive drugs that have questionable benefits, such as medications to treat dementia and statins to lower their cholesterol levels." According to the article, "In the study published Monday in JAMA Internal Medicine, Tjia and her colleagues examined medical records of 5406 nursing home residents with advanced dementia in 460 facilities across the United States from 2009 to 2010. They found that nearly 54 percent received at least one medication that was of questionable benefit usually because their doctor had declined to take them off of it when their symptoms worsened over time."
  • A September 8, 2014 CBS News article reported that UCLA biologists say they have identified a gene that can slow the aging process when activated. According to the article, "AMPK has been shown to activate a process of discarding old, damaged cellular components. That process, called autophagy, can prevent further damage to cells. Many neurodegenerative diseases, including both Alzheimer’s and Parkinson’s, are associated with the build-up of protein aggregates, a type of cellular garbage, in the brain. “Instead of studying the diseases of aging — Parkinson’s disease, Alzheimer’s disease, cancer, stroke, cardiovascular disease, diabetes — one by one, we believe it may be possible to intervene in the aging process and delay the onset of many of these diseases,” Walker said. “We are not there yet, and it could, of course, take many years, but that is our goal and we think it is realistic.”"